DNMT3B System Dysregulation Contributes to the Hypomethylated State in Ischaemic Human Hearts
A controversial understanding of the state of the DNA methylation machinery exists in ischaemic cardiomyopathy (ICM).Moreover, its relationship to other epigenetic alterations is incomplete.Therefore, we carried out an in-depth study of the DNA methylation process in human cardiac tissue.We showed a dysregulation of the DNA methylation machinery ac